Telomerase activity in “suspicious” thyroid cytology
نویسندگان
چکیده
منابع مشابه
Implications of a suspicious afirma test result in thyroid fine-needle aspiration cytology: an institutional experience.
BACKGROUND Fine-needle aspiration (FNA) biopsy is the most frequently used method for thyroid nodule evaluation. However, up to 30% of cases are considered indeterminate. Surgery is typically recommended for these cases, but up to two-thirds of indeterminate cases are found to be benign. The Afirma test is used for the preoperative classification of thyroid nodules with indeterminate cytology. ...
متن کاملUsefulness of preoperative serum calcitonin in patients with nodular thyroid disease without suspicious history or cytology for medullary thyroid carcinoma.
OBJECTIVE To evaluate the usefulness of preoperative serum calcitonin (sCT) in patients with nodular disease without suspicion of medullary thyroid carcinoma (MTC) in history or cytology. PATIENTS AND METHODS sCT was measured before thyroidectomy in 494 patients with nodular disease who had no family history of MTC or multiple endocrine neoplasia type 2, and no cytological suspicion of MTC. ...
متن کاملHuman telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors.
PURPOSE Patients with a preoperative cytologic diagnosis of a suspicious thyroid nodule present a therapeutic dilemma because surgery differs for benign and malignant lesions. To address this issue, several molecular markers, including human telomerase reverse transcriptase (TERT), have been tested as markers of thyroid cancer. Because most studies select cases falling into well-defined categor...
متن کاملMalignancy risk assessment in adenomatoid nodules and suspicious follicular lesions of the thyroid obtained by fine needle aspiration cytology.
Our aim was to assess malignancy risk in adenomatoid nodules and suspicious follicular lesions of the thyroid obtained by fine needle aspiration (FNA) cytology. Retrospective research was performed of 276 patients who underwent thyroid surgery after preoperative ultrasound-guided FNA diagnosis of either adenomatoid nodule, cellular follicular lesion, "suspicious for follicular neoplasm" or foll...
متن کاملThyroid nodules with highly suspicious ultrasonographic features, but with benign cytology on two occasions: is malignancy still possible?
OBJECTIVE There is no information about the frequency of malignancy specifically in the case of thyroid nodules with highly suspicious sonographic features, but with two fine needle aspiration (FNA) showing benign cytology. This was the objective of the study. SUBJECTS AND METHODS We report the results of 105 patients with thyroid nodules considered "highly suspicious" according to the ultras...
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ژورنال
عنوان ژورنال: Cancer
سال: 2005
ISSN: 0008-543X
DOI: 10.1002/cncr.21380